If this methods dont work, try this one. If you have sider, run PES 2021 WITHOUT it first. After PES 2021 is running, it will detect your controller and you can control it without any problems. Close the game, then you can run the sider before PES 2021 (The controller will work perfectly). Hope this help you, cause it worked for me. (You can setting the controllers from the setting option in PES 2021 folder).